Study the potential association between Toxoplasma gondii , HBV and HCV in tuberculous patients
Keywords:
Toxoplasma, hepatitis B virus (HBV), hepatitis C virus (HCV) TB patientsAbstract
Two obligatory intracellular infectious microorganisms include Toxoplasma gondii and Mycobacterium tuberculosis. The microbe T. gondii is the source of the parasitic disease Toxoplasmosis, whereas hepatitis B and C viruses are a viral infection known for its ability to damage the liver. The hepatitis B and hepatitis C viruses are the foundation of the severe type of hepatitis disease .The current study's objectives are to investigate the toxoplasma and hepatitis B and C virus (hepatitis B and hepatitis C viruses) infection in addition to identify any possible correlation between the two in TB patients compared to those who apparently healthy. Methodology: This is a case-control study. It was conducted between July 2022 and February 2023 at the Chest and Respiratory Disease Specialized Center in Baghdad under fully aseptic circumstances. Samples were taken from a hundred tuberculosis patients and a control group. The recognition depends on Anti-Toxoplasma IgG and Anti -hepatitis B virus (HCV and HBV) in their serums via using Toxoplasma IgG enzyme-linked immunosorbent assay kit ELISA technique. The current study's findings conclude that the occurrence of antitoxoplasma IgG among tuberculosis patients and control group was (58%) and(16%), respectively. P=0.0006 indicates a statistically significant difference in the measurement of Toxoplasma infection in the middle of tuberculosis patients and control group. The research showed that, in contrast control group 1 (2%), 7 (14%) and 5 (10%) of TB patients tested positive for HBV and HCV, respectively. When comparing TB patients and the control group, it was demonstrated that there was a significant difference (P<0.01) between T. gondii/HBV and T. gondii/HCV of 28.5% and 60%, respectively
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